A sleek genome, except for all the junk.(Brief Article)

Wolbachia pipientis is a biological eye opener. This intracellular bacterium that colonizes insects and filarial nematodes kills male hosts but thrives in females, sometimes even influencing sexual determination. The recent completion of the W. pipientis genome reveals another unique quality: A streamlined genome without the loss of mobile elements and junk DNA.

"This finding was an enormous surprise," says Jonathan Eisen, investigator at the Institute for Genomic Research, Rockville, Md., who together with Scott O'Neill, from the University of Queensland, Australia, formed a consortium to sequence the organism in 1999. Evolutionary forces typically shrink the genomes …