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COPYRIGHT 2004 International Medical News Group
WASHINGTON -- Antipruritic therapy in patients with atopic dermatitis should combine peripherally acting anti-inflammatories, immunomodulating agents, moisturizers, and centrally-acting inhibitors, Dr. Gil Yosipovitch said at the annual meeting of the American Academy of Dermatology.
Until recently, inflammation was thought to be primarily responsible for itch. Now, new pathophysiologic research suggests that there is "cross talk" between the stratum corneum and the nervous system. Damage to the skin barrier induces secretion of a variety of chemical mediators and neuropeptides, which in turn induces...
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