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Urea, ciclopirox combination tested for onychomycosis: boosting drug entry into nails.(Dermatologic Therapy)
Publication: Skin & Allergy News Publication Date: 01-APR-04 Author: Zoler, Mitchel L.
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COPYRIGHT 2004 International Medical News Group
WASHINGTON -- Combination treatment of onychomycosis using two topical preparations--40% urea gel and 8% ciclopirox lacquer--resulted in 100% mycologic cure in a pilot study with 18 patients.
The application of urea prior to ciclopirox may improve penetration of the antifungal agent into the nail plate and thereby boost ciclopirox's efficacy, Dr. Jeffery C. Weeks said while presenting a poster at the annual meeting...
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