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Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis serotypes L1, L2 and L3. Unlike other serotypes (A to K), those that cause LGV are invasive and preferentially target lymph tissue. LGV can be transmitted through vaginal, anal or oral sexual contact and can be prevented through the use of condoms or other barrier methods.
LGV infection begins with a small, painless lesion (which may go unnoticed) and can progress to painful enlargement of local lymph nodes, which may coalesce to form a bubo. (1) If the infection is left untreated, lymphatic obstruction may result, which can lead to serious complications, such ...