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INSECTS AS MODEL SYSTEMS FOR NEURONAL DEVELOPMENT AND REPAIR MECHANISMS.
An experimental drug, PDMP, has been shown to block metastasis by inhibiting the display of carbohydrates on tumor cell surfaces. Further work with PDMP and related drugs to prevent the spread of cancer now seems justified. This (University of Arizona) work is intended to show that rapidly growing insect nerve cells can serve as a model for cancer in humans, and that simple assays based on this approach should permit the testing of a large number of new drugs based on PDMP. Drugs that ...
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