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Exercise, antiresorptives help breast cancer survivors' BMD. (Pilot Study).
HONOLULU -- Breast cancer survivors who took antiresorptive medications and participated in a home strength and weight training exercise program made more gains based on bone mineral density measurements than women who only took medications, according to the findings of a University of Nebraska study.
The pilot study of 21 postmenopausal breast cancer survivors was persuasive enough to generate funding from the National Institutes of Health for a larger trial aimed at reducing osteoporosis in former breast cancer patients; these patients are often advised against taking hormone replacement therapy because their cancers were estrogen-receptor positive.
The initial trial, led by Nancy Waltman, Ph.D., of the University of Nebraska Medical Center College of Nursing in Lincoln, recruited stage I or II breast cancer patients whose treatments other than tamoxifen had concluded at least 6 months previously. The mean age of the participants was 54, with a range of 42-65.
Results were reported at an international symposium sponsored by the National Osteoporosis Foundation.
At baseline, 3 subjects had a normal bone mineral density (BMD), 14 were osteopenic, and 4 had previously undiagnosed osteoporosis.
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