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High levels of osteopontin may flag ovarian ca. (Could Speed Detection).

OB GYN News

| June 01, 2002 | Rudd, Terry | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Cancerous ovarian tissue cells may produce significantly higher levels of osteopontin protein than their healthy counterparts, a finding that eventually could help clinicians detect ovarian cancer sooner, said Dr. Jae-Hoon Kim of the Catholic University of Korea, Suwon, and associates.

The researchers compared osteopontin levels in a benchmark healthy ovarian epithelial cell culture with those of 4 other healthy ovarian epithelial cell cultures, 10 serous-type ovarian epithelial cancer cell lines, 2 mucinous-type ovarian cancer cell lines, and 2 clear cell-type ovarian cancer cell lines. They also compared preoperative osteopontin levels in plasma from a total of 251 patients: 51 with ...

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