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Observational Tx acceptable in stage IC endometrial cancer. (No Adjuvant Radiation Therapy).
MIAMI BEACH -- Adjuvant radiation therapy did not improve overall survival in a study of stage IC endometrial cancer patients, Dr. J. Michael Straughn Jr. reported at the annual meeting of the Society of Gynecologic Oncologists.
These findings, viewed together with the lack of prospective studies suggesting any survival benefit with adjuvant radiation therapy in stage IC endometrial cancer patients, support observational therapy as an acceptable option in these patients. This is particularly true when the side effects, complications, costs, and adverse effects on quality of life associated with radiation therapy are taken into account, said Dr. Straughn of the University of Alabama in Birmingham.
A retrospective chart review of 220 patients with endometrial cancer identified via tumor registries at four institutions revealed that 6 (6%) of 99 patients who were surgically staged and treated with adjuvant brachytherapy, whole-pelvic radiation therapy or a combination of both had recurrence in the median 35-month follow-up period.
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Source: HighBeam Research, Observational Tx acceptable in stage IC endometrial cancer. (No...