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Sensitivity of only 9%: no place for nasal bone evaluation by ultrasound in aneuploidy screening.(Obstetrics)
NEW ORLEANS -- First-trimester nasal bone evaluation by ultrasound appears to be nearly useless in identifying aneuploidy, with a sensitivity of only 9%, Dr. Fergal Malone said at the annual meeting of the Society for Maternal-Fetal Medicine.
Although the absence of nasal bones is an extremely uncommon finding on ultrasound, it was not significantly associated with the presence of either trisomy 18 or 21, said Dr. Malone of New York-Presbyterian Hospital, New York, a coinvestigator in the First-and Second-Trimester Evaluation of Risk for Aneuploidy (FASTER).
"Nasal bone evaluation failed to identify even one case of trisomy 21 in this population," he said. "This form of screening has virtually no role in screening for aneuploidy in the general population."
Nasal bone images were obtained from 6,316 FASTER patients during the final 7 months of the trial; 45 sonographers, each of whom had received additional training in imaging nasal bones, performed the scans.
Each scan was examined by a second specially trained sonographer, who certified the scan as acceptable or unacceptable. Acceptable images had to show the fetus in a midsagittal plane with the spine down and had to be enlarged enough to show two echogenic nasal lines--a superficial line showing the nasal skin and a ...
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...of her fetus's nasal bones, Dr. Ants Toi...British study of nasal bone hyoplasia at 15...fewer hypoplastic nasal bones, compared with...difference in fetal nasal bone length by quartile...had fetuses whose nasal bones were about 0...
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- Magazine article from: The Scientist Lewis, Ricki January 7, 2002 700+ words
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- Magazine article from: OB GYN News Boschert, Sherry February 1, 2003 700+ words
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- Magazine article from: OB GYN News Walsh, Nancy February 1, 2002 700+ words
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- Magazine article from: GP December 7, 2001 700+ words
...month that checking for the presence of a nasal bone during routine antenatal ultrasound scanning...on the premise that the absence of a nasal bone in a fetus at 11-14 weeks indicates...profile for the presence or absence of a nasal bone during a nuchal translucency scan, and...
- Estudio craneometrico de los huesos nasales y proceso frontal de la Maxila.
- Magazine article from: International Journal of Morphology Costa, Jecilene Rosana Prates, José Carlos Traber de Castillo, Helton de Almeida Santos, Rafael March 1, 2005 700+ words
...the nose) and width of nasal bones (width of nasal dorsum...being male measures of nasal bones and frontal process of maxilla...KEY WORDS: Craniometry; Nasal bone; Maxilla. Craniometric Study of Nasal Bones and Frontal Processes of...
Source: HighBeam Research, Sensitivity of only 9%: no place for nasal bone evaluation by...