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NEW ORLEANS -- Women with systemic lupus erythematosus are more likely than other women to experience a stillbirth and to give birth before term, despite recent advances in lupus treatment, Dr. Robert Sokol reported in a series of posters presented at the annual meeting of the Society for Maternal-Fetal Medicine.
But the 17-year study of pregnancy outcomes in women with lupus did show two encouraging trends: a slight decrease in the stillbirth rate of these infants; and an indication that, although they are still more likely to be born early, the infants are growing better in utero.
"Although these trends weren't statistically significant, they were still apparent," said Dr. Sokol of Wayne State University, Detroit. "We think this reflects improvements in technology, medical care, and treatment of lupus. We're intervening earlier and more aggressively and getting better outcomes."
Dr. Sokol presented the results of Dr. Patricia Dahr's cohort analysis of 327 women with lupus. Dr. Dahr, also of Wayne State, compared the first pregnancy of each patient in the lupus group to the first pregnancy of each patient in a control group of 78,905 women without the disease.
Women with lupus were four times more likely than controls to experience a stillbirth. ...