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Hormone therapy trials halted due to evidence of health risks.
Byline: Judy Peres
CHICAGO _ Researchers have halted a large, nationwide study of hormone replacement therapy after discovering that the pills now being taken by millions of postmenopausal women cause breast cancer, heart attacks and other serious side effects.
The absolute risk is small: Only about 1 percent of the women who took estrogen plus progesterone during the five years of the study had a problem. Nevertheless, the study authors concluded, if you're thinking of taking HRT in hopes of preventing heart disease _ don't.
Many doctors were swamped by calls from patients suddenly forced to reassess whether to continue taking drugs that make them feel better _ and which they had been led to believe might be good for them.
HRT is usually prescribed to treat hot flashes and other symptoms of menopause and to prevent osteoporosis, and doctors said it's still appropriate for those purposes. But the study shows it would not be justified for long-term use in a woman with mild or no symptoms whose rationale for taking it was to improve her overall health.
The chances of this study being contradicted in a few months by another piece of research are slim: This was a huge, well-designed, well-controlled…
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Source: HighBeam Research, Hormone therapy trials halted due to evidence of health risks.
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