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Persistent C. trachomatis may foster malignancies. (Lingering Genital Infection).
SAN FRANCISCO -- Persistent Chlamydia trachomatis infection in the genital tract may induce susceptibility to gynecologic malignancies, Dr. Steven S. Witkin said at the annual meeting of the Infectious Diseases Society of America.
There is good evidence that genital tract chlamydial infections can persist for a long time, even after clinically successful antimicrobial therapy.
To learn whether persistent infection is associated with development of gynecologic cancers, Dr. Witkin looked for IgA antibodies to C. trachomatis in endocervical samples obtained from 96 women being evaluated for possible gynecologic malignancies.
Cervical IgA antibodies were selected as the investigative target because they have a short half-life. Detection of these antibodies would suggest C. trachomatis persistence in the genital tract, explained Dr. Witkin, who is an ob.gyn. at Cornell University in New York.
Blinded testing revealed the presence of cervical IgA antibodies to C. trachomatis in 18 of the 62 women (29%) who were shown to have a gynecologic malignancy and in none of the 34 with a benign ...
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Introduction Genital tract malignancies are one of the most...the threshold for decreasing gynecologic malignancies and increasing survival. Assessment...relative frequency of female genital tract malignant tumors and to explore...
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- Novel T cell population has strong regulatory role in mouse female genital...
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...strong regulatory role in mouse female genital tract. "A better understanding of the regulatory role of genital tract T cells is much needed. In this...function of T lymphocytes in the female genital tract of naive, pregnant, or Chlamydia...
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...associated with an increased risk of genital tract shedding of herpes simplex virus type...colonization are two of the most common genital tract conditions present among women of reproductive...associations between these variables and genital tract shedding of HSV-2 would result in...
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...DIEGO -- Repeat screening for lower genital tract infections in pregnant adolescents...screening of adolescents for common genital tract infections will improve their obstetric...particularly in their risk of lower genital tract infections." In an ongoing study...
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...NewsRx.com & NewsRx.net) -- Genital tract shedding of HIV is linked to an increased...To determine the association between genital tract shedding of human immunodeficiency...03)." "The cell-associated genital tract compartment is important in the pathophysiology...
- Genital tract viral shedding linked to increased risk.
- Magazine article from: Women's Health Weekly March 20, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Genital tract shedding of HIV is linked to an increased...To determine the association between genital tract shedding of human immunodeficiency...03)." "The cell-associated genital tract compartment is important in the pathophysiology...
Source: HighBeam Research, Persistent C. trachomatis may foster malignancies. (Lingering Genital...