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Stage I Uterine Papillary Ca often recurs. (Largest Case Series).
ASHLAND, ORE. -- Even early-stage uterine papillary serous carcinoma patients had a high rate of recurrence in a study of 100 cases of this aggressive form of endometrial cancer.
Among 35 patients with stage I or stage II disease, half were found to have extrapelvic involvement during an average 2.5 years of follow-up, "suggesting at least the need for addressing adjuvant therapy" in this group, Dr. Steven A. Vasilev said at the annual meeting of the Pacific Coast Obstetrical and Gynecological Society.
Dr. Vasilev analyzed tumor registry data, surgical logs, and associated patient records of patients diagnosed with uterine papillary serous carcinoma (UPSC) from 1985 to 2000 at two institutions.
A total of 100 patients were identified: 26 with stage I disease, 9 with stage II disease, 25 with stage III disease, and 20 with stage IV disease. In 20 patients, complete surgical staging was not performed, said Dr. Vasilev, director of gynecologic oncology at the Kaiser Permanente Los Angeles Medical Center.
With a median age of 67 years, the UPSC patients were older on average than were patients diagnosed with other forms of endometrial cancer. Postmenopausal bleeding was the presenting symptom in 85 patients; the remainder had pelvic pain. A number of other lessons can also be inferred from ...
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Source: HighBeam Research, Stage I Uterine Papillary Ca often recurs. (Largest Case Series).