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M. genitalium tied to pelvic inflammatory disease: sexual transmission.(Gynecology)
OTTAWA--Growing evidence linking Mycoplasma genitalium and pelvic inflammatory disease shouldn't be ignored, Dr. Jonathan Ross said at a congress of the International Society for Sexually Transmitted Disease Research.
This pathogen has been recognized for two decades as a cause of nongonococcal urethritis in men, but only recently have studies begun to suggest an association with upper genitourinary tract disease in women, said Dr. Ross of the Whitall Street Clinic, Birmingham, England.
Much of the evidence has been indirect. "We know that M. genitalium can attach to fallopian tube cells in vitro, so there is the potential for inflammation. We also know that it can cause damage because tubal infertility has been reported in infected women," he said.
Historically, the organism has been difficult to detect because it is fastidious and slow growing. But the availability of polymerase chain reaction (PCR) testing is now permitting rapid, accurate detection and clarifying its role as a disease causing pathogen.
Other presentations supported his assertion that this pathogen can cause pelvic inflammatory disease (PID). In 50 women with nongonococcal, nonchlamydial endometritis, M. genitalium was detected in 7 (14%) women, in 6 cervical specimens and 4 endometrial specimens, said Catherine L. Haggerty. Ph.D. Chronic endometritis was identified in 3 (75%) of the ...
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Source: HighBeam Research, M. genitalium tied to pelvic inflammatory disease: sexual...