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Fruit cocktail.(Letters)(Letter to the Editor)
Publication: Natural History Publication Date: 01-MAR-05 Author: Dominy, Nathaniel J. ; Rhodes, Justin S. ; Crabbe, John C. ; Ginsberg, David ; Dudley, Robert
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COPYRIGHT 2005 Natural History Magazine, Inc.
In "The Drunken Monkey Hypothesis" (12/04-1/05) Dustin Stephens and Robert Dudley suggest that human alcoholism is rooted in the evolutionary history of primates. They reason that frugivorous primates evolved mechanisms for tolerating dietary ethanol because low levels of alcohol are characteristic of ripe fruits.
It is compelling supporting evidence for the hypothesis that approximately 10 percent of the total soluble protein in the human liver is alcohol dehydrogenase, one of the enzymes that metabolizes alcohol. But it is also important to consider how primates recognize ethanol,...
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