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Do major drug companies that pay for the testing of new medicines control the design of the studies--and, more importantly, do they tell participating researchers how to handle the findings? Yes to both questions, a recent survey of 108 medical schools has found.
The survey, which appears in the October 24, 2002 issue of the New England Journal of Medicine (NEJM), increases concern about conflicts of interest between scientists who do research and pharmaceutical companies who sponsor it.
Some scientists worry that researchers' lack of control could threaten the integrity of studies and the safety of test volunteers. Also, the study found that some companies have suppressed the results of sponsored research that found a drug didn't work or was dangerous.
In 2001, concern over this issue led the International Committee of Medical Journal Editors to publish guidelines for research contracts between medical schools and pharmaceutical companies. However, the new study by Duke University concluded that few research contracts comply with the guidelines.
The ...