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SAN FRANCISCO -- The use of chronic corticosteroids has become so popular that "we might as well put it in the drinking water," Dr. Mary Frank remarked at the annual meeting of the California Academy of Family Physicians.
But patients--especially young asthmatics--are paying a big price: a threefold risk of bone fracture due to osteoporosis.
"We're really getting control of asthma and control of allergic symptoms with inhaled steroids, but it turns out that inhaled steroids are just as bad as oral steroids when it comes to the risk of osteoporosis," said Dr. Frank, a family physician who is medical director of Primary Care Associates of Rohnert Park (Calif.). "It might take you longer to get there, but you're still going to get there."
Intranasal corticosreroids also can increase bone loss, but only if the daily doses are 1,000-2,000 [micro]g or more.
Bone loss does not occur with low-dose intranasal corticosteroids, she said.
In general, fractures occur in 25%-40% of patients on chronic corticosteroid therapy. The most common fracture is vertebral, but the risk of hip fracture also rises sharply.
To help prevent corticosteroid-induced osteoporosis, use the lowest effective dose for the shortest effective ...