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Uterine rupture risk was 3-15 times higher with VBAC than elective C-section.
The recent finding that vaginal birth after cesarean section increases the risk of uterine rupture up to 15 times may curb patients' willingness to attempt VBAC, experts predicted.
In a study that analyzed records of 20,095 women, researchers found that, compared with those who had a repeat elective cesarean section, the rate of uterine rupture was 3.3 times higher among women who went into spontaneous labor, 4.9 times higher among those whose labor was induced without prostaglandins, and 15.6 times higher if prostaglandins were used.
The study "certainly is going to have a chilling effect" on the overall VBAC rate, not just prostaglandin-induced VBACs, Dr. Roger Freeman, who chaired the American College of Obstetricians and Gynecologists Task Force on the Evaluation of Cesarean Delivery, said during an interview.
The retrospective cohort analysis compared the rate of uterine rupture among women who had a previous C-section and were giving birth to their second singleton child. (See chart, page 2.)
The women gave birth in Washington state hospitals from 1987 through 1996, said Mona Lydon-Rochelle, Ph.D., and her associates at the University of Washington in Seattle (N. Engl. J. Med. 345[1]:3-8, 2001).
"There's no doubt that elective repeat section had the least uterine ruptures, but the rate was still very low among the non-induced VBAC patients," Dr. Luis Sanchez-Ramos told this newspaper. Based on the data, he calculated that one would have to pefform up to 625 repeat cesarean deliveries to prevent one uterine rupture.
Source: HighBeam Research, Study May Have 'Chilling Effect' On VBAC Rate.