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Migraine Prophylaxis.
There is little evidence-based information about selecting prophylactic drug strategies for migraine headache, Dr. Neil H. Raskin said at the annual meeting of the American Headache Society.
Evidence is weak at best for the efficacy of the two drug classes with the least noxious side effect profiles--calcium channel antagonists and the newer anticonvulsants. Yet despite a paucity of controlled trials, these drugs do have some less-rigorous evidence behind them, said Dr. Raskin of the University of California, San Francisco.
He stated his preference for starting patients on the new calcium channel antagonist amlodipine because of its bland side effect profile. It avoids the weight gain seen in patients on valproate, 40% of whom gain as much as 50-60 pounds.
Dr. Raskin suggested starting with an amlodipine dosage of 2.5 mg/day and increasing it gradually to 7.5-12.5 mg/day. He occasionally goes as high as 15 ...
- Migraine prophylaxis.(DRUG UPDATE)(Treatment of migraine prophylaxis)
- Magazine article from: Internal Medicine News Mechcatie, Elizabeth Finn, Robert February 1, 2006 700+ words
...might benefit from migraine prophylaxis are actually receiving...medications for migraine prophylaxis fall into a surprising...blockers, and calcium channel antagonists...effective for migraine prophylaxis in randomized...
- Migraine prophylaxis.(Drug Update)
- Magazine article from: Skin & Allergy News Finn, Robert February 1, 2006 700+ words
...benefit from migraine prophylaxis are actually...medications for migraine prophylaxis fall into...blockers, and calcium channel antagonists...day)] CALCIUM CHANNEL ANTAGONIST...effective for migraine prophylaxis in randomized...
- Petasites, tizanidine boost migraine prophylaxis. (Roundup of Investigational...
- Magazine article from: Family Practice News Jancin, Bruce June 1, 2002 700+ words
...hybridus, for migraine prophylaxis. After 4 months...possibly via calcium channel regulation...effective for migraine prophylaxis in a 56-week...weight loss, migraine prophylaxis doses are low...
- Comorbid conditions can guide migraine prophylaxis.(DATA WATCH)
- Magazine article from: OB GYN News April 15, 2005 700+ words
...Comorbid Conditions Can Guide Migraine Prophylaxis Side Relative Drug Efficacy...Raynaud's disease, diabetes Calcium Channel Blockers Verapamil 2+ 1...Blockers Hypertension, angina Calcium Channel Blockers Verapamil Migraine...
- Comorbid conditions can guide migraine prophylaxis.(DATA WATCH)(Chart)
- Magazine article from: Clinical Psychiatry News October 1, 2005 700+ words
...Comorbid Conditions Can Guide Migraine Prophylaxis Side Drug Efficacy* Effects...beta]-Blockers 4+ 2+ Calcium Channel Blockers Verapamil 2+ 1...Raynaud's disease, diabetes Calcium Channel Blockers Verapamil Constipation...
- Newer drugs no better for migraine prophylaxis.(Neurology)
- Magazine article from: Internal Medicine News Wachter, Kerri August 1, 2008 700+ words
...Washington -- Newer drugs aren't any better for migraine prophylaxis than are older treatments and may be worse choices...blockers (nadolol, metoprolol, atenolol), calcium-channel blockers (verapamil, nifedipine), an anticonvulsant...
- Frequency, disability must guide migraine prophylaxis.(Pain Medicine)
- Magazine article from: Clinical Psychiatry News Dixon, Bruce K. March 1, 2007 700+ words
...timolol both have class A evidence and lie in group 1. All of the calcium channel blocking agents available in the United States have class B scientific evidence. Calcium channel blockers are the drugs of choice for hemiplegic migraine and basilar...
- Biofrontera has successfully completed a first human trial with its migraine...
- News wire article from: Europe Intelligence Wire February 26, 2007 700+ words
...completed a first human trial with its migraine prophylaxis compound BF-1. The study revealed...severe migraine. "We believe that migraine prophylaxis is a potential block-buster market...which we expect to be effective in migraine prophylaxis without any relevant adverse side...
- A randomized double-blind placebo-controlled trial of thioctic acid in migraine...
- Magazine article from: Alternative Medicine Review Magis, D. Ambrosini, A. Sandor, P. June 1, 2007 700+ words
...or coenzyme Q, are effective in migraine prophylaxis and quasi-devoid of adverse effects...thioctic acid (Thioctacid) in migraine prophylaxis steered by the Belgian Headache...thioctic acid may be beneficial in migraine prophylaxis. Before any firm conclusion can...
- Butterbur for migraine prophylaxis.(Alternative medicine: an evidence-based...
- Magazine article from: Family Practice News Walsh, Nancy March 15, 2005 700+ words
...and a small study of 60 patients suggested efficacy in migraine prophylaxis, researchers in New York and Germany undertook a double...head to head studies comparing petasites to feverfew for migraine prophylaxis, Dr. Lipton said, "in my judgment the evidence for...
Source: HighBeam Research, Migraine Prophylaxis.