AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Cox-2 Drugs Differ in Effect on Blood Pressure.
ORLANDO, FLA. -- Rofecoxib was associated with an increase in mean systolic blood pressure, but celecoxib was not, in a randomized trial of the cyclooxygenase-2 inhibitors in arthritic patients with treated hypertension.
Celecoxib-treated patients were also less likely to develop clinically significant edema. And when they did develop edema, blood pressure rose substantially less than in edematous rofecoxib-treated patients, Dr. William B. White said at the annual meeting of the American College of Cardiology.
An estimated 12 million Americans with hypertension have comorbid arthritis and are therefore at risk for developing renal side effects if they take antihypertensive drugs along with conventional nonselective NSAIDs. These are patients likely to be using cyclooxygenase-2 (COX-2) inhibitors.
If rofecoxib tends to worsen blood pressure control in those patients and celecoxib does not, that's a practical consideration, according to Dr. White, who serves on the speakers' bureau for Merck & Co., manufacturer of the drug, ...
- You Can Lower the Blood Pressure 10 mm Hg with Diet Alone!
- Magazine article from: Internal Medicine Alert February 28, 2001 700+ words
You Can Lower the Blood Pressure 10 mm Hg with Diet Alone! Abstract &...There was a reduction of 8.9 mm Hg in systolic blood pressure and 4.5 mm Hg in diastolic blood pressure between the high and low sodium intake...
- Hypertension treatment in the elderly needs careful scrutiny: octogenarians may...
- Magazine article from: Heart Advisor Vidt, Donald June 1, 2009 700+ words
...pressure (SBP) of less than 140 mm Hg and a diastolic blood pressure (DBP) of less than 90 mm Hg...HYVET study had a higher baseline blood pressure of 173/91 mm Hg, and the target blood pressure in the treatment group was 150...
- High, low BP bad for stroke patients: poor outcomes more likely in those with...
- Magazine article from: Renal & Urology News Schieszer, John July 1, 2006 700+ words
...relationship between initial blood pressure and short-term functional...defined high BP as a MAP of 130 mm Hg or higher and low BP as a MAP of 90 mm Hg or less. The investigators...Patients with MAPs above 130 mm Hg and below 90 mm Hg were three...
- Systolic target of 135 mm Hg cuts diabetes mortality: deaths reduced by 14%,...
- Magazine article from: Internal Medicine News Zoler, Mitchel L. September 15, 2007 700+ words
...an average systolic blood pressure of 135 mm Hg. The treatment also...argument" in favor of a blood pressure target of 130 mm Hg for patients with diabetes...the mean systolic blood pressure was 135/75 mm Hg in the active arm and...
- Adjust treatment goals in hypertensive seniors: in patients with coronary...
- Magazine article from: Family Practice News Zoler, Mitchel L. April 1, 2007 700+ words
...those who maintained a blood pressure of less than 120/80 mm Hg had a significantly...to avoid excessive blood pressure lowering in this population...said in their poster. Blood pressure that is less than 120/80 mm Hg in older patients with...
- Diastolics Below 80 mm Hg Lower Stroke Risk.(Statistical Data Included)
- Magazine article from: Family Practice News GOLDMAN, ERIK L. April 1, 2000 700+ words
...diastolic pressures over 90 mm Hg confer a significant increase...diastolic pressure below 80 mm Hg. "The optimal poststroke blood pressure is not really known," said...have been decreased to below 80 mm Hg," Dr. Friday noted. In that...
- Systolic BP tied to mortality in kidney disease.(Nephrology)(blood pressure)
- Magazine article from: Internal Medicine News Walsh, Nancy December 15, 2008 700+ words
...patient level of systolic blood pressure (110-129 mm Hg, 130-159 mm Hg, or...patients with systolic blood pressure below 130 mm Hg, the high tertile having...patients with systolic blood pressure above 160 mm Hg, and the middle ...
- Study Shows Nighttime Dosing of Biovail's Cardizem LA Lowers Blood Pressure and...
- Press release article from: Business Wire May 16, 2003 700+ words
...significantly greater drop in diastolic blood pressure (-10 mm Hg) versus Altace(R) (-7 mm Hg). Systolic blood pressure reductions were similar over...have hypotension (less than 90 mm Hg systolic blood pressure), hypersensitivity to ...
