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Vitamin C reduces levels of a marker for inflammation--a protein that has been more strongly linked to heart disease than cholesterol levels.
A University of California, Berkeley, study reported in the April 2004 issue of the Journal of the American College of Nutrition shows that daily doses of 500 milligrams (mg) of vitamin C lower C-reactive protein (CRP) levels by 24 percent after 2 months.
The vitamin C must be taken by itself. Patients receiving an antioxidant containing vitamins C and E and alpha-lipoic acid experienced no significant CRP reduction. No one knows why, but it's possible that an interaction among the antioxidants rendered the mixture less effective.
High CRP readings indicate inflammation, which is increasingly blamed for heart disease in some people who have healthy levels of cholesterol and triglycerides. In fact, a large number of heart attack victims previously tested low for cholesterol.
CRP is also linked to diabetes and Alzheimer's disease risk.
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