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Raloxifene Doesn't Improve Cognition.

OB GYN News

| June 15, 2001 | Moon, Mary Ann | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

The selective estrogen-receptor modulator raloxifene doesn't appear to improve cognitive function in postmenopausal women, but it may delay cognitive decline, reported Dr. Kristine Yaffe of the University of California, San Francisco, and associates.

As part of a larger study on raloxifene's effects on osteoporosis, Dr. Yaffe and her associates assessed the cognitive performance of 7,478 postmenopausal women over the course of 3 years (N. Engl. J. Med. 344[16]:1207-13, 2001).

The women were randomly assigned to receive 60 mg of raloxifene, 120 mg of raloxifene, or a placebo daily. They ...

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