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Researchers at the Dana-Farber Cancer Institute and Brigham and Women's Hospital recently discovered a gene in mice that seems to cause them to undergo early menopause--a condition similar to one that afflicts some 250,000 women in the United States.
During the study, scientists examined mice that lacked copies of the Foxo3a gene--a member of the forkhead gene family. Forkhead genes are regulators, which turn other genes on and off. They're believed to control processes related to aging, cancer and diabetes. Researchers observed that female mice that lacked the gene had fewer and smaller litters than those with the gene--and that the gene-less mice were sterile ...