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Methyldopa a Safe Antihypertensive During Pregnancy.

OB GYN News

| June 01, 2001 | Jancin, Bruce | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

VAIL, COLO. -- Methyldopa is an old and frequently overlooked agent that, in the setting of hypertension in pregnancy, is suddenly transformed into first-line therapy, Dr. Jill Davies said at a conference on obstetrics and gynecology sponsored by the University of Colorado.

"Aldomet [methyldopa] is a category B medication. It has the longest safety record for treatment of hypertension in pregnancy. So even though outside of pregnancy it's not even close to being considered a first-line agent, we still consider it first-line therapy in pregnancy because of its safety record," said Dr. Davies of the university.

The most problematic class of antihypertensive agents in pregnancy are the angiotensin-converting enzyme inhibitors. They are ...

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