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SOUTH LAKE TAHOE, NEV. -- Comprehensive surgical staging of endometrial cancer with lymph node evaluation can identify high-risk patients who could benefit from radiation therapy, Dr. Anthony H. Russell said at an obstetrics and gynecology conference sponsored by the University of California, Davis.
Some have questioned the merits of comprehensive surgical staging in endometrial cancer because of concerns that it leads to increased morbidity. There also has been debate over whether adjunctive radiation therapy can increase survival.
Radiation has an important place in the treatment of uterine cancer, said Dr. Russell, a radiation oncologist from Sacramento. Although studies of adjunctive radiation therapy after surgery have generally shown that radiation has only very modest benefit in the aggregate, an unpublished study conducted by the Gynecology Oncology Group suggests that the benefit may be greater among high-risk patients.
In the study, 390 surgically staged endometrial cancer, patients were randomized to either radiation or no additional treatment. There was ...
Source: HighBeam Research, Comprehensive Surgical Staging Defended.