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Dendritic Cells Eyed for Cervical Cancer Vaccine.

OB GYN News

| May 01, 2001 | Kirn, Timothy F. | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SOUTH LAKE TAHOE, NEW. -- The use of harvested dendritic cells may be the key to producing a vaccine to treat cervical cancer, according to Dr. Ricardo Estape.

So far, research on the use of vaccines to treat cancer has run into serious and frustrating roadblocks, Dr. Estape said at an obstetrics and gynecology conference sponsored by the University of California, Davis.

But that has been because the peptides or viral particles used in the vaccines to provoke a response, when simply released into circulation, have not been taken up properly by antigen-presenting cells of the immune system. The result has been an induction of a B-cell-mediated humor response rather than a T-cell-mediated cellular response, which is the more important response for cancers and viral infection, said Dr. Estape of the department of gynecologic oncology at the University of Miami.

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Source: HighBeam Research, Dendritic Cells Eyed for Cervical Cancer Vaccine.

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