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TORONTO -- Researchers who transplanted a cervical cancer patient's ovary into her forearm last year have now successfully stimulated ovulation and retrieved oocytes from it, according to the head of the team.
However, they were unsuccessful in fertilizing an egg to create an embryo.
"I think it's just a matter of time because we've come so close. Our egg retrieval and stimulation techniques still need to be perfected," Dr. Kutluk Oktay told this newspaper.
Last year the patient had her ovaries removed before radiotherapy to treat cervical cancer. They transplanted one of the ovaries into her forearm before the radiation treatment.
The procedure of oocyte retrieval from the transplanted ovary was initially performed in an unstimulated cycle, using a standard retrieval needle percutaneously, under local anesthesia.
The attempt was largely unsuccessful, yielding only one fractured oocyte from an 11-mm follicle, said Dr. Oktay of Cornell University, New York.
However, for the second attempt, the patient underwent ovarian stimulation, and three immature oocytes were retrieved.
Source: HighBeam Research, Transplanted Ovary Ovulates; Oocytes Retrieved.