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New HIV treatment guidelines are on track regarding recommendations to delay initial antiretroviral therapy, new research findings confirm.
The treatment guidelines from the Department of Health and Human Services aim to balance the long-term adverse effects of antiretroviral therapy against the benefits of early viral control. The guidelines advise patients to delay antiretroviral therapy until CD4 counts fall below 350 cells/ mL.
The findings of a study of more than 1,000 patients indicate that CD4 counts may need to dip below 201 cells /[micro]L before highly active antiretroviral therapy (HAART) significantly reduces disease progression.
Dr. Timothy Sterling of Johns Hopkins University, ...