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Zoladex Before Ablation Leads to Better Outcomes.
ORLANDO, FLA. -- Pretreatment with goserelin acetate improves long-term outcomes in patients undergoing endometrial ablation for dysfunctional uterine bleeding, a recent study found.
The 358 premenopausal patients in the study were treated with either placebo or 3.6 mg of depot goserelin acetate (Zoladex). Two injections were given 28 days apart. The procedure was performed about 6 weeks after the first injection, Dr. George A. Vilos reported at the annual meeting of the American Association of Gynecologic Laparoscopists.
Amenorrhea rates at a 6-month follow up were 40% in the goserelin acetate group and 26% in the placebo group. At 1 year, the rates were 35% and 22%; at 3 years, they dropped to 21% in the goserelin acetate group and 14% in the placebo group.
"There was a reduction in the amenorrhea rate in both groups, but it appears Zoladex is still holding. It fares a little better [than placebo]," said Dr. Vilos of the ...
- Goserelin acetate had a very low response rate with subcutaneous delivery.
- Newspaper article from: Clinical Trials Week February 24, 2003 700+ words
...designed to estimate the activity of goserelin acetate as treatment for advanced and recurrent...patients received monthly treatment with goserelin acetate at a dose of 3.6 mg, given subcutaneously...confirmed the limited activity of goserelin acetate in endometrial carcinoma, with ...
- Goserelin acetate had a very low response rate with subcutaneous...
- Newspaper article from: Cancer Weekly February 25, 2003 700+ words
...designed to estimate the activity of goserelin acetate as treatment for advanced and recurrent...patients received monthly treatment with goserelin acetate at a dose of 3.6 mg, given subcutaneously...confirmed the limited activity of goserelin acetate in endometrial carcinoma, with ...
- GOSERELIN ACETATE.
- Magazine article from: Chemical Market Reporter August 3, 1998 700+ words
GOSERELIN ACETATE Implant- FDA has approved Zeneca Pharmaceuticals' Zoladex (goserelin acetate implant) in combination with anti-androgen flutamide prior to and during radiation therapy in the treatment of prostate cancer.
- Adding ZOLADEX(R) (Goserelin Acetate Implant) Therapy to Standard Radiotherapy...
- Press release article from: PR Newswire November 1, 1999 700+ words
...PRNewswire/ -- Hormonal therapy with Zoladex(R) (goserelin acetate implant), a product of AstraZeneca, in patients with...for the treatment of prostate cancer, Zoladex(R) (goserelin acetate implant) and CASODEX(R) (bicalutamide) Tablets...
- JAPAN GOVT TENDER - GOSERELIN ACETATE.
- News wire article from: AsiaPulse News February 9, 2000 700+ words
...PULSE TENDER ***** KUSHIRO ROSAI HOSPITAL TO PROCURE GOSERELIN ACETATE AND OTHER The following is a procurement notice published...Nature and quantity of the products to be purchased ; (i) Goserelin Acetate 1 vial (3.6mg (as Goserelin)) 440 vials (ii) Granisetron...
- Biovail to Promote AstraZeneca's Zoladex(R) 3.6mg (Goserelin Acetate Implant)...
- Press release article from: Business Wire May 2, 2006 700+ words
...Pharmaceuticals LP have entered into an agreement for which BPI's specialty sales force will promote Zoladex(R) 3.6mg (goserelin acetate implant) to obstetricians and gynecologists for the treatment of endometriosis in the United States and Puerto Rico...
- AstraZeneca Receives Six Months Pediatric Exclusivity for CASODEX(R)...
- Press release article from: PR Newswire September 22, 2008 700+ words
...launched in 1995, and ZOLADEX(R) (goserelin acetate implant), launched in 1989. Three...prostateinfo.com/. About ZOLADEX(R) (goserelin acetate implant) ZOLADEX 3.6 mg depot...occurred during treatment with ZOLADEX (goserelin acetate implant) plus flutamide and radiation...
- Researchers from Marmara University, Medical Department report on findings in...
- Newspaper article from: Blood Weekly April 23, 2009 700+ words
...the first dose of GnRH agonist, Goserelin Acetate (Zoladex(A (R)), subcutaneous...1.1 +/- A 0.3 ng/ml after Goserelin acetate treatment (P = 0.005). Significant...Research, Fibrinolysis, Gonadotropin, Goserelin Acetate, Hematology, Hormones, Metastatic...
