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Memo
As a first-line drug therapy, acetaminophen is effective only for mild osteoarthritis pain without inflammation, according to evidence-based-guidelines released at the annual meeting of the American Pain Society.
New guidelines on the treatment of arthritis pain put a strong emphasis on early use of nonsteroidal antiinflammatory drugs (NSAIDs) and disease-modifying antirheumatic drugs (DMARDs), even before the use of acetaminophen.
Patients with inflammation or moderate to severe pain caused by osteoarthritis or rheumatoid arthritis should receive early treatment with selective NSAIDs, such as the cydooxygenase-2 (COX-2) inhibitors celecoxib (Celebrex) or rofecoxib (Vioxx), the ...