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Histologic patterns may reveal stage, prognosis of endometriosis. (May Help Predict Response to Therapy).

OB GYN News

| May 01, 2002 | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SAN DIEGO -- Endometriosis with an undifferentiated or mixed histologic pattern was more often associated with stage III-IV disease, more severe pain before treatment, and a less favorable prognosis after treatment, compared with endometriosis showing a stromal or well-differentiated histologic pattern, a recent study suggests.

Based on these findings, histologic classification of endometriosis may help predict response to treatment, Dr. Mauricio S. Abrao said at the World Congress on Endometriosis.

He and his associates at Sao Paulo (Brazil) University applied the four histologic classifications to 412 endometrial biopsies taken from 241 patients treated for endometriosis over a 6-year period. They compared results with the medical records of the patients, all of whom underwent surgical treatment followed by 6 months of therapy with the GnRH analogue goserelin. Patients were observed for up to 1.5 years.

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Source: HighBeam Research, Histologic patterns may reveal stage, prognosis of endometriosis....

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