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SAN DIEGO -- A majority of 50 postmenopausal women diagnosed with endometriosis had no previous history of the disease, a review of cases treated over a 5-year period at one institution found.
Endometriosis is not just a disease of the childbearing years. When pelvic pain, adnexal masses, and other typical signs and symptoms of endometriosis in menopausal or postmenopausal women are present, the disease may indeed be present, Dr. Ash Dabbous said in a poster presentation at the World Congress on Endometriosis.
A total of 42% of these patients were not on hormone replacement therapy (HRT), illustrating that exogenous hormones are not necessary for endometriosis to develop postmenopausally, added Dr. Dabbous, an ob.gyn. at the University of Texas, San Antonio.
In general, endometriotic lesions are believed to depend on estrogen for proliferation and to regress in the absence of ovarian function. There have been previous reports, however, of symptomatic endometriosis recurring in oophorectomized women who were not on HRT.
An estimated 2%-4% of endometriosis cases are ...