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Observation called for in HIV-positive women who have low-grade SIL. (Treatment Likely to Fail).
SEATTLE -- HIV-infected patients with low-grade cervical squamous intraepithelial lesions can be observed in the same manner as other patients, even though their chances are much lower for lesion regression, Dr. Tedd V Ellerbrock said at the Ninth Conference on Retroviruses and Opportunistic Infections.
In a study of 122 HIV-infected women and 257 uninfected women with biopsy-confirmed squamous intraepithelial lesions (SILs), the rates of progression from low-grade to high-grade SIL were not significantly different between infected and uninfected women. Consequently, observation was prudent, especially considering the study also revealed that SIL treatment is much more likely to fail in HIV patients, said Dr. Ellerbrock of the Centers for Disease Control and Prevention, Atlanta.
Patients with high-grade SIL were randomized to either cryotherapy or a loop electrosurgical procedure (LEEP).
Low-grade SIL patients were randomized to either observation or cryotherapy. The mean time of follow-up was 10-11 months, he commented at the conference, sponsored by the Foundation for Retrovirology and Human Health.
The rate of ...
- Three algorithms summarize management of low-grade SIL.
- Newspaper article from: Obesity, Fitness & Wellness Week June 26, 2004 700+ words
...common basis for the management of low-grade SIL," wrote C. Scheungraber and colleagues...with the cytologic diagnosis of low-grade SIL." From these, the physicians were...define three general algorithms for low-grade SIL management: "Variant 1 was proposed...
- HPV genotyping of high-grade SIL may have prognostic value.
- Newspaper article from: Cancer Weekly December 28, 2004 700+ words
2004 DEC 28 - (NewsRx.com & NewsRx.net) -- Human papillomavirus (HPV) genotyping of high grade squamous intraepithelial cervical lesions may help determine risk of progression to invasive carcinoma. "High-grade squamous intraepithelial lesions of the cervix are heterogeneous in their invasive
- LETTERS.(Brief Article)
- Magazine article from: Family Practice News December 1, 2000 700+ words
...group. Of the SIL smears, most were low-grade SIL (2.5%); 0.7% had high-grade SIL with no cancer detected. It makes sense...than 1% of Paps in adolescents had high-grade SIL in the Mount study; and (4) the progression...
- Physicians Too Aggressive on ASCUS Follow-Up.(Brief Article)(Statistical Data...
- Magazine article from: Family Practice News BOSCHERT, SHERRY March 1, 2000 700+ words
...I was taught that your pickup rate for high-grade SIL is going to be much higher if you wait for the...times higher than the cumulative rate of low-grade SIL plus high-grade SIL diaguoses. "If your ASCUS rate is 20% and your...
- Physicians Too Aggressive on ASCUS Follow-Up.(interpreting Pap test results)
- Magazine article from: OB GYN News BOSCHERT, SHERRY March 1, 2000 700+ words
...I was taught that your pickup rate for high-grade SIL is going to be much higher if you wait for the...times higher than the cumulative rate of low-grade SIL plus high-grade SIL diagnoses. "If your ASCUS rate is 20% and your...
- High-risk HPV types: risk of SIL greater in lupus patients.(News)
- Magazine article from: OB GYN News Walsh, Nancy September 1, 2004 700+ words
...and therapeutics, Prince of Wales Hospital, Hong Kong. High-grade SIL, in which cellular abnormalities are more pronounced and less likely to be transient than in low-grade SIL, was detected in 3.7% of lupus patients and in 0.5% of...
- HPV Test Not Set to Replace Cervical Cytology.
- Magazine article from: Family Practice News February 15, 2000 700+ words
...collected vaginal sample for detecting cervical cancer or high-grade SIL was 66.1%, comparable to the 60.7% sensitivity of a...with 96.8% for specimens when smears diagnosed as low-grade SIL or higher were considered positive. These specificity findings...
- Significance of Atypical Glandular Cells of Undetermined Significance on...
- Magazine article from: OB/GYN Clinical Alert November 1, 2000 700+ words
...of the evaluation, three patients were found to have low-grade SIL changes, four high-grade, three adenocarcinoma in situ...certainly much more worrisome for invasive cancer than a high-grade SIL lesion, and I should probably stop preaching. The fact remains...
Source: HighBeam Research, Observation called for in HIV-positive women who have low-grade SIL....