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Reevaluate Necessity of Anticonvulsants in Pregnancy.
SARASOTA, FLA. - Epileptics who are on anticonvulsant therapy during pregnancy have a 5% risk of fetal malformations, which is double the risk seen in the general population, Dr. Jennifer R. Niebyl said at a perinatal symposium sponsored by Symposia Medicus.
The most common birth defects in this group are cleft lip / cleft palate and congenital heart defects. In addition, 1% of epileptic women treated with valproic acid during pregnancy will have a baby with neural tube defects, and 5%-10% of fetuses exposed to hydantoin will have fetal hydantoin syndrome, which includes microcephaly growth deficiency developmental delays and mental retardation, dysmorphic craniofacial features, and hypoplasia of nails and distal phalanges.
Despite this, it is well recognized that the benefits of anticonvulsant therapy in pregnancy outweigh the risks as long as the therapy is truly necessary said Dr. Niebyl, professor and head of the department of obstetrics and gynecology at the University of Iowa in Iowa City.
For this reason, she strongly recommends that women with epilepsy who are ...
- Anticonvulsant therapy causes vitamin D deficiency.(Literature Review &...
- Magazine article from: Townsend Letter: The Examiner of Alternative Medicine Gaby, Alan R. November 1, 2007 700+ words
...two adults (aged 18-54 years) and 78 children and adolescents (aged ten to 18 years) on long-term anticonvulsant therapy were randomly assigned to receive low-dose (400 IU/day) or high-dose (4,000 IU/day for adults...
- Effects of anticonvulsant therapy on vitamin D status in children: prospective...
- Magazine article from: Alternative Medicine Review Nicolaidou, P. Georgouli, H. Kotsalis, H. December 1, 2006 700+ words
...D, parathyroid hormone, calcium, and phosphorus levels were determined before and every 3 months during anticonvulsant therapy. Our subjects were grouped into four classes (0, 1, 2, and 3 consisted of the patients before and during...
- Reevaluate Anticonvulsant Use In Pregnant Epilepsy Patients.
- Magazine article from: Family Practice News JOHNSON, KATE May 15, 2001 700+ words
...FLA. -- Epileptics who are on anticonvulsant therapy during pregnancy have a 5% risk...recognized that the benefits of anticonvulsant therapy in pregnancy outweigh the risks...to confirm their true need for anticonvulsant therapy "Some patients may have been put...
- GP BUSINESS: Ensuring quality in epilepsy.
- Magazine article from: GP October 6, 2003 700+ words
...frequency. To achieve this all patients currently taking anticonvulsant therapy will require an annual review with proper recording...a register of patients who are currently prescribed anticonvulsant therapy. This 'quality cohort' is a dynamic list that may...
- Biotin.(Monograph)
- Magazine article from: Alternative Medicine Review March 1, 2007 700+ words
...extended parenteral nutrition, pregnancy, or long-term anticonvulsant therapy. Conditions that may benefit from biotin supplementation...biotin for 14 days. (17) Individuals on long-term anticonvulsant therapy are also at high risk for a biotin deficiency (see...
- First Anti-Epileptic Drug in Extended Release Formulation Available to Patients...
- Press release article from: PR Newswire August 20, 1996 700+ words
...pretreatment hematologic testing as a baseline. As with all anticonvulsant therapy, periodic hematologic evaluations are recommended at...levels during conversion to Tegretol-XR or whenever any anticonvulsant therapy formulation is changed. See enclosed package insert...
- Vitamin D supplements might prevent anticonvulsant-induced bone disease.
- Newspaper article from: Biotech Week May 19, 2004 700+ words
...can be recommended for all patients on initiation of anticonvulsant therapy. A calcium intake of 600-1000 mg/day should also...of bisphosphonates in patients receiving long-term anticonvulsant therapy cannot at present be recommended." Drezner and colleagues...
- Neuropsychiatric symptoms are varied and tend to occur at disease onset.
- Newspaper article from: Clinical Trials Week March 17, 2003 700+ words
...NPSLE responded well to high dose corticosteroids. Anticonvulsant therapy could be discontinued within a median duration of 3...Seizures, Disease Onset, Corticosteroid Therapy, Anticonvulsant Therapy, Autoimmune Disease and Immunology. This article was...
- Tegretol(R)-XR receives clearance for marketing.
- Press release article from: Business Wire May 2, 1996 700+ words
...pretreatment hematologic testing as a baseline. As with all anticonvulsant therapy, periodic hematologic evaluations are recommended at...levels during conversion to Tegretol-XR or whenever any anticonvulsant therapy formulation is changed. Tegretol-XR will be marketed...
- New anticonvulsants--new adverse effects.
- Magazine article from: Southern Medical Journal Tebb, Zachary Tobias, Joseph D. April 1, 2006 700+ words
...a seizure disorder. The patient had been receiving anticonvulsant therapy since discharge from the neonatal ICU at a gestational...no history of seizure activity following discharge. Anticonvulsant therapy initially included phenobarbital (7.2 mg b.i...
Source: HighBeam Research, Reevaluate Necessity of Anticonvulsants in Pregnancy.