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Could be nonsurgical diagnostic tool: Two cytokines may flag possible endometriosis. (Gynecology).
SAN DIEGO -- A study of six cytokines in blood and peritoneal fluid identified two that could compose the first nonsurgical tool for diagnosing endometriosis.
Investigators compared concentrations of the six cytokines-interleukin -- 1[beta] (IL-1[beta]), IL-6, IL-8, IL-12, IL-13, and tumor necrosis factor-[alpha] (TNF[alpha])--in blood and peritoneal fluid obtained from women undergoing diagnostic laparoscopy for pain, infertility, tubal ligation, or sterilization reversal.
Only serum IL-6 and pentoneal fluid TNF-[alpha] showed a high sensitivity and specificity in differentiating the 56 women given a postsurgical diagnosis of endometriosis from the 8 women diagnosed with unexplained infertility and from the control group of 27 women who underwent tubal ligation or reanastomosis, Dr. Mohamed A. Bedaiwy said at the World Congress on Endometriosis.
Serum IL-6 concentrations of 2 pg/mL or higher diagnosed endometriosis with a sensitivity of 90% and a specificity of 67%. With a cut-off value of 7.5 pg/mL, the sensitivity was 80% and the ...
- Interleukin concentrations vary in peritoneal fluid of women with endometriosis.
- Newspaper article from: Blood Weekly June 17, 2004 700+ words
...Significantly higher peritoneal fluid IL-12 levels were found in...endometriosis showed remarkably lower peritoneal fluid IL-13 concentrations than...direct correlation between peritoneal fluid T cells and IL-12 concentrations." Investigators...
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...underwent surgery. Peritoneal fluid detected on a CT scan...regression identified peritoneal fluid detected on a CT scan...Conclusion: The presence of peritoneal fluid on a CT scan in patients...surgery. Contexte : Il est difficile de predire...
- Peritoneal fluid macrophages jumpstart endometrial inflammation.
- Magazine article from: Women's Health Weekly April 22, 2004 700+ words
...NewsRx.net) -- Peritoneal fluid macrophages jumpstart...the United States, "peritoneal fluid macrophages (PFM) are...influence of interleukin (IL)-1beta and other macrophage...Gynecology. "The addition of IL-1 receptor antagonist...
- Laparoscopy for peritoneal fluid.(Causes and Treatment)
- Clinical Reference Systems January 1, 2006 700+ words
What is a laparoscopy? A laparoscopy is a procedure in which your health care provider uses a laparoscope to look at the organs and tissues inside your peritoneal cavity. A laparoscope is a thin, lighted tube. The peritoneal cavity is the space that holds most of your abdominal and pelvic organs.
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- Magazine article from: Nephrology Nursing Journal Desai, Bijal Dahl, Naomi Steward, Caroline Sherman, Richard April 1, 2001 700+ words
Bijal Desai MD, Naomi Dahl PharmD, Caroline Steward RN MSN, Richard Sherman MD. University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
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...These data demonstrate that this IL-12 gene therapeutic is safe...treated with higher dosages. IL-12 plasmid was detectable in peritoneal fluid of all evaluable patients and...predominant cytokine activated by IL-12, in all patients. "We...
- Scientists at Medical University of Warsaw discuss research in endometriosis...
- Magazine article from: Women's Health Weekly December 18, 2008 700+ words
...and inflammatory cytokines (IL-1beta, IL-6, IFN-gamma and TNF) in peritoneal fluid were evaluated by specific...Leptin concentrations in peritoneal fluid correlated negatively with concentrations of IL-1beta and IFN-gamma...
- New sepsis study findings have been published by scientists at Cincinnati...
- Newspaper article from: Blood Weekly October 9, 2008 700+ words
...subsequent CLP. Lung tissue, peritoneal fluid, and blood were collected...plasma TNF-alpha and IL-6 at 6 h after CLP. Peritoneal fluid cytokines were significantly...clearance in both blood and peritoneal fluid after CLP. Similarly...
Source: HighBeam Research, Could be nonsurgical diagnostic tool: Two cytokines may flag possible...