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BRCA mutations boost risk of tubal cancer. (Survey of 44 Patients).

OB GYN News

| April 15, 2002 | Jancin, Bruce | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

VAIL, COLO. -- Fallopian tube cancer appears to be a part of the hereditary breast-ovarian cancer syndrome associated with BRCA1 and BRCA2 mutations, Dr. Susan A. Davidson said at a conference on obstetrics and gynecology sponsored by the University of Colorado.

Multiple prior isolated reports of a possible link between fallopian tube cancer and BRCA1 and BRCA2 mutations prompted Ontario Cancer Registry officials to conduct the first-ever survey of unselected cases of fallopian tube cancer.

Of the 44 participating patients with fallopian tube carcinoma, 5 (11%) proved to have a BRCA1 mutation, and 2 (5%) had a BRCA2 mutation, said Dr. Davidson, chief of the division of gynecologic oncology at the university in Denver.

Noting that mutations of BRCA1 or BRCA2 account for only 5%-10% of cases of ovarian cancer, she added that "potentially ...

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Source: HighBeam Research, BRCA mutations boost risk of tubal cancer. (Survey of 44 Patients).

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