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Cancidas.
(caspofungin acetate, Merck)
An antifungal for treating invasive aspergillosis in people who don't respond to or can't tolerate other antifungal treatments, including amphotericin B. This is the first agent in a new class of antifungals, the echinocandins or glucan synthesis inhibitors, to be approved.
* Recommended Dosage: A loading IV dose of 70 mg, followed by 50 mg IV once a day; duration of treatment depends on response and other factors.
* Special Considerations: In trials of more than 600 patients and healthy volunteers, the most common side effects included fever, infused vein complications, nausea, vomiting, and flushing, each reported in almost 3% of subjects. Not ...
- Treatment with Cancidas(TM) Resulted in Favorable Response for Many Patients...
- Press release article from: PR Newswire September 18, 2000 700+ words
In Vitro Study with Cancidas Also Showed Antifungal Activity...showed that treatment with Cancidas(TM) (caspofungin acetate...diagnosed with life-threatening invasive aspergillosis who were not responding to...49 percent (22 of 45). Cancidas is an echinocandin known...
- Caspofungin--a new antifungal agent.(for the treatment of invasive...
- Newspaper article from: Physician's Therapeutics & Drug Alert Elliott, William T. Chan, James October 1, 2001 700+ words
...trade name Cancidas. Indication...treatment of invasive aspergillosis in patients...candidiasis and invasive aspergillosis, (6) however...treating invasive aspergillosis refractory...References (1.) Cancidas Product Information...
- FDA Panel Unanimously Recommends Vfend.(acute invasive aspergillosis...
- Magazine article from: Chemical Market Reporter October 15, 2001 700+ words
...voriconazole) in intravenous and oral forms to treat acute invasive aspergillosis. Pfizer launched schizophrenia drug Geodon (ziprasidone...differentiation for its dual administration. Merck's Cancidas might be relegated to patients who have failed amphotericin...
- Invasive aspergillosis in immunocompetent patients.(Letter to the editor)
- Magazine article from: Southern Medical Journal Blot, Stijn I. Vandewoude, Koenraad H. December 1, 2006 700+ words
...1) As the authors state, invasive aspergillosis is mainly encountered in patients...with the authors' statement that invasive aspergillosis occurs almost exclusively in patients...immune function. Evidence that invasive aspergillosis is an emerging opportunistic infection...
- Invasive aspergillosis treated with adjunctive hyperbaric oxygenation: A...
- Magazine article from: Southern Medical Journal Garcia-Covarrubias, Lisardo Barratt, Diana M. Bartlett, Robert Metzinger, Stephen Meter, Keith Van April 1, 2002 700+ words
Background. Invasive aspergillosis Is the leading cause of...histologic specimens suggested invasive aspergillosis. Our main assessment of...role. ********** INVASIVE ASPERGILLOSIS is the leading cause of...
- Treatment of Invasive Aspergillosis: To Combine or Not to Combine?
- Magazine article from: Infectious Disease Alert December 1, 2004 700+ words
Treatment of Invasive Aspergillosis: To Combine or Not to...Antifungal Therapy For Invasive Aspergillosis. Clin Infect Dis. 2004...with probable or proven invasive aspergillosis who failed treatment with...
- SciClone's ZADAXIN Demonstrates Significant Anti-Fungal Efficacy in Invasive...
- Press release article from: Business Wire March 1, 2004 700+ words
...effective anti-fungal treatment for invasive aspergillosis. The study showed that ZADAXIN...ZADAXIN alone were fully cured of invasive aspergillosis. Additionally, it was observed...with ZADAXIN in a mouse model of invasive aspergillosis. About Aspergillus fumigatus The...
- Posaconazole Salvage in Invasive Aspergillosis.(Report)
- Newspaper article from: Hospital Medicine Alert Deresinski, Stan March 1, 2007 700+ words
...Posaconazole Salvage in Invasive Aspergillosis Abstract & Commentary...et al. Treatment of invasive aspergillosis with posaconazole in...Salvage therapy of invasive aspergillosis with posaconazole was...
