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PALM SPRINGS, CALIF. -- Improvement in sexual function resulting from the antidepressant effects of fluoxetine appears to be more common than drug-associated deterioration in sexual function, Dr. John Plewes II reported during the annual meeting of the Academy of Psychosomatic Medicine.
Dr. Plewes and his associates conducted a multicenter trial of 501 men and women aged 18-80 years who met DSM-IV criteria for depression. Prior to starting the 13-week treatment regimen, they completed a four-item self-report assessment of sexual interest/desire, vaginal lubrication/erection, orgasm, and overall sexual function, said Dr. Plewes, who presented the findings on behalf of the primary investigator, Dr. David Michelson, a clinical research physician with Lilly Research Laboratories, Indianapolis.
Patients initially were evaluated at baseline and again after 13 weeks of fluoxetine (Prozac) 20 mg daily Responders went on to receive 25 weeks of continuation therapy with either fluoxetine 20 mg daily, ...
Source: HighBeam Research, Sexual Functioning Improves in 52% Of Depressed Women on Fluoxetine.