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Two Studies Offer Conflicting Findings on Utility of Cerclage for Cervical Shortening.
RENO, NEV. -- There's no clear answer yet to the question of whether cerclage improves neonatal outcome when cervical shortening is identified on second-trimester ultrasonography, Dr. Orion Rust said in the final session of the annual meeting of the Society for Maternal-Fetal Medicine.
Two randomized studies presented earlier in the meeting, one from the Netherlands and the second from Dr. Rust's group at Lehigh Valley Hospital in Allentown, Pa., had reached conflicting conclusions.
In the Cervical Incompetence Prevention Randomized Cerclage Trial, which was presented by Dr. Sietske Althuisius of Free University Hospital, Amsterdam, therapeutic cerclage reduced the occurrence of preterm delivery and neonatal morbidity. In the Allentown study, which was presented by Dr. Robert Atlas, no improvements were seen in gestational age at delivery or in overall neonatal outcome.
The Amsterdam study included 35 women at high risk of preterm delivery because of a history of preterm delivery; their cervical length was shorter than 25 mm. Nineteen of the patients were randomized to therapeutic cerclage and bedrest and 16 to bedrest only.
At delivery, the mean gestational age in the bedrest-only group was 33 1/7 weeks, which was significantly earlier than the 37 6/7 weeks seen in the cerclage group. None of the patients in the cerclage group delivered before ...
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Source: HighBeam Research, Two Studies Offer Conflicting Findings on Utility of Cerclage for...