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Nuchal Fold Test Flags Fetal Defects.
RENO, NEV. -- First-trimester nuchal translucency measurement proved to be a "reasonably sensitive" means of identifying aneuploidy in high-risk patients in a metaanalysis presented at the annual meeting of the Society for Maternal-Fetal Medicine.
In a poster session, Dr. Ellen Mozurkewich analyzed 27 studies including 163,450 subjects and reported that nuchal translucency measurements identified 78% of fetuses affected by trisomy 21, 82% of those with trisomy 18, 90% of those with trisomy 13, and 96% of those with monosomy X.
The negative predictive value for all four conditions was 99%. The false-positive rate for each of the conditions was less than 5%.
The current standard of care in the United States is for women aged 35 and older to be offered amniocentesis or chorionic villi sampling to screen for aneuploidy, but many women decline the invasive testing or request second-trimester ultrasound or biochemical screening before making a decision on invasive testing, said Dr. Mozurkewich of the University of Michigan, Ann Arbor. ...
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- Magazine article from: Family Practice News WALSH, NANCY April 1, 2001 700+ words
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- Magazine article from: OB GYN News Sullivan, Michele G. September 15, 2002 700+ words
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- Magazine article from: Family Practice News DONOHUE, MAUREEN January 15, 2000 700+ words
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- Possible screening tool; Chromosomally normal fetuses: nuchal translucency,...
- Magazine article from: OB GYN News Sullivan, Michele G. March 1, 2004 700+ words
...chromosomally normal fetus with increased nuchal translucency is at significantly heightened risk...Medicine. Each millimeter increase in nuchal translucency doubles the risk of a fetal congenital...Maternal Serum Biochemistry and Fetal Nuchal Translucency Screening (BUN) Study ...
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- Magazine article from: OB GYN News Worcester, Sharon June 1, 2003 700+ words
...relationship between first-trimester nuchal translucency measurements and second-trimester...on a review of randomly selected nuchal translucency measurements (from the Cornell...ultrasound images) in euploid fetuses. Nuchal translucency had been measured between 11 and...