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PROM Mortality Rates Drop Over Last 10 Years.
BEAVER CREEK, COLO. -- Perinatal mortality in infants born following premature rupture of the membranes before 28 weeks' gestation has declined significantly over the past decade, from a rate of 41% in the early 1990s to 19% between 1998 and 2000, Dr. John D. Yeast said during a perinatal conference sponsored by the University of California, Irvine.
In addition, the mortality rate associated with premature rupture of membranes (PROM) before 25 weeks and a period of latency to delivery of more than 14 days fell from 91% in the early 1990s to 25% in 1998-2000, said Dr. Yeast, director of maternal-fetal medicine at St. Luke's Perinatal Center, Kansas City, Mo.
He compared perinatal mortality rates in 81 women with PROM who were seen at St. Luke's from 1998 to 2000 with that in 108 such women seen between 1992 and 1993. Dr. Yeast had reported data on this second group of women previously (Am. J. Obstet. Gynecol. 175[3]:175-81, 1996).
Analysis of the data suggests that mortality is related to gestational age, duration of ruptured membranes, and severity of oligohydramnios, but that no single variable predicts outcome.
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Source: HighBeam Research, PROM Mortality Rates Drop Over Last 10 Years.