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The use of isotretinoin tar acne does not raise a patient's risk for depression, suicide, or neurotic and psychotic symptoms, reported Susan S. Jick, Sc.D., of the Boston Collaborative Drug Surveillance Program, Lexington, Mass., and her associates.
Anecdotal reports of a link between isotretinoin and adverse psychiatric symptoms have been highlighted in the media, causing widespread concern among clinicians and patients, the researchers said.
They assessed two population-based databases to determine the relative risks of such disorders among isotretinoin users, compared with acne ...