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Ultrasound Under Study as Treatment for Breast Ca.

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| February 15, 2001 | JOHNSON, KATE | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

CHICAGO -- An ultrasound technique could become a treatment option for breast cancer patients, according to researchers at St. Luc Hospital, Montreal.

Dr. David Gianfelice reported that 17 of 22 breast cancer patients (77%) are tumor free after undergoing one or two treatments with an investigational ultrasound treatment. The approach is also under study at Brigham and Women's Hospital in Boston, M.D. Anderson Cancer Center in Houston, and Stanford (Calif.) University. The Montreal center has the most experience of the four.

The new technique is known as magnetic resonance-guided focused ultrasound ablation (MR-FUS). The equipment used in the treatment is not yet approved in the United States. It is being tested for a variety of indications besides treatment of breast tumors.

Dr. Gianfelice's study was funded in part by the equipment's manufacturer, TXSonics Ltd. of Haifa, Israel, but Dr. Gianfelice has no financial involvement in the company.

"I'm certainly not here to tell you [MR-FUS] is going to replace breast surgery but it could certainly become another option for some breast cancer patients," he told this newspaper at the annual meeting of the Radiological Society of North America

All patients underwent a single session of MR-FUS ablation and were then followed with MRI and radiologic assessment of the breast to determine the treatment response and to rule out any metastatic disease.

At 6 months post treatment, all study participants underwent multiple core biopsies of the treated area to evaluate whether any residual tumor existed, and a second treatment was scheduled only if necessary.

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