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New Papillomavirus Target Could Lead to First Specific Antiviral Drugs for Precancerous Cervical Lesions.
Byline: Harvard University Medical School
BOSTON, April 29 (AScribe Newswire) -- Harvard Medical School researchers have uncovered a missing link in our understanding of how human papillomaviruses gain their foothold in the rapidly dividing cells of the skin and mucous membranes. The discovery, reported in the April 30 Cell, could lead to new treatments for a host of human papillomavirus-related conditions, from the nuisance of plantar and genital warts to life-threatening precancerous cervical lesions.
"We have uncovered a new target that could potentially lead to new antivirals. There is certainly a need because there are no specific human papillomavirus antivirals out there at this point," said Peter Howley, the Shattuck professor of pathological anatomy at HMS.
Unlike some viruses-such as influenza, HIV, and the common cold virus-which churn out copies within the confines of a single host cell that is then destroyed, human papillomaviruses invade proliferating epithelial cells and distribute their copies among subsequent generations.…
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Source: HighBeam Research, New Papillomavirus Target Could Lead to First Specific Antiviral...
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