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Chemical Exposure Can Hasten Puberty in Girls.

OB GYN News

| February 01, 2001 | JOHNSON, KATE | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

A chemical accident in Michigan in the early 1970s has resulted in early menarche among girls who were exposed to polybrominated biphenyls, either in utero or through their mother's breast milk.

More than 4,000 Michigan residents were exposed to polybrominated biphenyls (PBBs) through meat and dairy products when the chemicals were accidentally mixed with animal feed in 1973 (Epidemiology 11[6]:641-47, 2000).

This is the second study to associate early puberty with exposure to a specific chemical.

In the current study, scientists at Emory University, the Centers for Disease Control and Prevention, and the Michigan Department of Community Health contacted females aged 5-24 years whose mothers' PBB exposure was documented in a Michigan PBB exposure registry.

Girls with the highest exposure to PBBs--a chemical used in fire retardants--developed pubic hair and began menstruating on average before age 12.

The authors found no influence of the chemical on the girls' breast development.

The amount of exposure to PBBs did make a difference. Girls with the most exposure started menstruating about a year earlier than less-exposed girls--at age 11.6 years vs. 12.7 years.

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