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HILTON HEAD ISLAND, S.C. -- Certain behaviors adopted by patients with urinary incontinence to cope with their disorder can often linger long after the disease has been successfully treated, Dr. Veronica Mallett said at the annual meeting of the American Urogyneco-logic Society.
"Patients may not trust the impact of their medication, and so still limit their social activities or make sure they are always near a bathroom," Dr. Mallett, who is a urogynecologist at Wayne State University Detroit, told this newspaper in an interview.
In a study of the quality of life of women taking an extended-release, once-daily formulation of tolterodine (Detrol) for overactive bladder, Dr. Mallett found that despite the medication's significant impact on certain symptoms of incontinence, patients reported no significant improvement in their social limitations, relationships, emotions, or general health perceptions.
"We would have anticipated that the treated group would have had a greater reduction in their social limitations, but it could be that it's too early to measure this kind of thing after only 12 weeks of treatment," commented Dr. Mallett, who is on the speakers' bureau for Pharmacia & Upjohn, the manufacturer of tolterodine.
In a randomized, double-blind, placebo-controlled, multinational trial, 410 women were treated for 12 weeks with extended-release tolterodine and 416 women were given placebo.
To be included in the study patients had to have bladder symptoms ...
Source: HighBeam Research, Social Limitations Linger After Incontinence Tx.