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Asians react differently to oral glucose test.(Obstetrics)

OB GYN News

| April 15, 2005 | Kirn, Timothy F. | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

RENO, NEV. -- Oral glucose challenge test results appear to have different values for patients of different ethnicity, reported Tania Esakoff, M.D.

Specifically, Asians may need to meet a higher threshold cutoff than whites before undergoing a 3-hour fasting glucose tolerance test to determine whether they have gestational diabetes, and African Americans need a lower cutoff, Dr. Esakoff and her colleagues wrote in a poster presented at the annual meeting of the Society for Maternal-Fetal Medicine.

The researchers reviewed the records of 14,565 pregnancies screened for gestational diabetes with the 50-g glucose loading test in ethnically diverse San Francisco. They then computed the sensitivities and false-positive rates based on study results and known results for fasting glucose tolerance testing.

The results show Asians tend to be more sensitive to an oral glucose challenge and therefore need a higher cutoff, said Dr. Esakoff of the University of California, San Francisco.

With the currently recommended cutoff of a serum-glucose level of 140 mg/dL, which is now used for everyone regardless of ethnicity, the test would have a sensitivity of 89% and a false-positive rate of 14% for Asian ...

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Source: HighBeam Research, Asians react differently to oral glucose test.(Obstetrics)

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