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Retrospective study shows hypothyroidism tied to lower breast Ca risk.(News)
Women treated for hypothyroidism were less likely to develop primary breast carcinoma--and more likely to have more indolent disease when they did develop cancer--than women with normal thyroid function in a retrospective, case-control study.
The findings "strengthen the possibility of a significant role of thyroid hormones on breast cancer biology," said Massimo Cristofanilli, M.D, and his associates at the University of Texas M.D. Anderson Cancer Center, Houston.
The investigators compared the medical records from 1,136 women with primary breast carcinoma with those of 1,088 healthy women who visited their breast cancer--screening clinic. Approximately 240 women reported having symptomatic primary hypothyroidism and thyroid supplementation before they were diagnosed with breast cancer or before their screening.
The prevalence of reported hypothyroidism was significantly greater in the control group, compared with the breast cancer group (15% vs. 7%).
Women with primary hypothyroidism had a 61% lower risk of developing invasive breast cancer, and women with breast cancer were ...
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Source: HighBeam Research, Retrospective study shows hypothyroidism tied to lower breast Ca...