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A research study has concluded that melatonin may stave off Alzheimer's disease. The American Chemical Society journal Biochemistry reported Dec. 11, 2001 that melatonin--a natural hormone commonly used to treat jet lag--reverses the formation of a protein complex that is typical of Alzheimer's disease.
In the study, researchers successfully blocked the formation of the protein amyloid beta, which is toxic to nerve cells, with melatonin. Quoted in a report released by the Dietary Supplement Information Bureau after the study was published, Dr. Miguel Pappolla of the USA Medical Center and the University of South Alabama in Mobile was cautiously optimistic. "These exciting findings mandate much more research before we can convincingly state melatonin can halt or prevent Alzheimer's disease," Pappolla says. Statistics from a 1993 survey pro-vided by the ...