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A birthing success, an ethical debate over genetic screening.(Knight Ridder Newspapers)

Knight Ridder/Tribune News Service

| March 01, 2002 | Flam, Faye | COPYRIGHT 2002 Knight-Ridder/Tribune News Service. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

PHILADELPHIA _ Is it ethical to use high-tech genetic selection to ensure that a child is born without an unwanted hereditary trait?

That question is roiling the medical world after Tuesday's announcement that a 30-year-old woman used genetic screening to avoid passing on a form of early-onset Alzheimer's disease to her baby daughter.

It marked the first use of such genetic testing to prevent that disease, and it raised questions about when, or if, medical science should intervene in a person's genetic makeup.

"There are some enormous ethical issues _ much bigger than with cloning," said Arthur Caplan, a medical ethicist at the University of Pennsylvania.

While scientists continue to discover ever more genes associated with different traits or diseases, society, Caplan said, has yet to decide when genetic screening is appropriate. Which traits are considered serious enough? "It gets to what we consider a disease," he said.

Cases such as the ...

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